Los Angeles serves as a West Coast hub for some of the best cruise destinations out of the U.S. With two convenient departure points— the Port of Los Angeles and the Port of Long Beach— cruisers can easily access trips ranging from tropical getaways in Mexico to scenic excursions along the Pacific Coast and even up to Canada. Whether you’re seeking a short weekend escape or an adventurous exploration of the Panama Canal, Hawaiian Islands, or even Tahiti, there are unforgettable experiences waiting for you.
7-night California Coast cruise with Princess Cruises
Fall is the perfect time to embark on a weeklong cruise up the California coast. This Princess Cruises itinerary covers San Francisco, San Diego, and Ensenada, Mexico. A highlight of the journey includes an overnight stay in San Francisco, giving travelers ample time to tour Alcatraz, explore Sausalito, enjoy dim sum in Chinatown, or sip wine in Sonoma’s picturesque wine country.
Upon arriving in San Diego, guests can visit the world-famous zoo or explore the vibrant atmosphere of Old Town. Ensenada offers its own array of activities such as zip-lining through the desert or snorkeling off the crystal-clear waters of the Todos Santos islands. The Discovery Princess, one of the newest ships on the West Coast, provides an array of culinary options and onboard amenities including fun fitness classes and stunning views from the ship’s expansive balconies.
Who should book: This sailing is ideal for couples, multigenerational families, and groups of friends looking for a balanced mix of active port experiences and relaxing onboard routines.
16-night Panama Canal cruise with Norwegian Cruise Line
In October 2025, Norwegian Cruise Line will launch the Norwegian Encore on a spectacular 16-night Panama Canal cruise.
Travelers will stop at exciting locales including Cabo San Lucas—renowned for kayaking and snorkeling—followed by a visit to Puerto Vallarta where options range from city tours to tequila tastings. The itinerary also includes Manzanillo and Acapulco before making way to the intriguing landscapes of Central America. The highlight? A breathtaking day spent navigating the iconic 40-mile Panama Canal.
The Norwegian Encore, launched in 2017, offers passengers six days at sea full of activities, from the Thermal Suite to delightful culinary experiences like dining at Onda by Scarpetta. Family-friendly features include a water park for children and teens, ensuring everyone has an engaging cruise experience.
Who should book: Ideal for retirees with flexible travel schedules or families wishing to take advantage of extensive amenities aboard.
5-night Cabo overnight cruise on Royal Caribbean
For a quick getaway, consider a five-night cruise with Royal Caribbean. With two sea days and an entire day in Cabo San Lucas, it’s perfect for relaxing. Enjoy beach activities, or go on a catamaran sunset cruise, while visiting iconic sites like El Arco.
The 4,900-passenger Ovation of the Seas will debut in June 2025, featuring attractions like the North Star—a viewing pod that lifts passengers above the ship’s deck—along with a plethora of dining options including Jamie’s Italian by Jamie Oliver. Nightlife on board can include outdoor movie nights or energetic theatrical performances.
Who should book: This cruise suits couples seeking romance, groups of friends celebrating special occasions, and young families alike.
18-night Los Angeles to Tahiti with Crystal
For luxury seekers, consider sailing on the Crystal Serenity with an 18-night cruise to Tahiti in January 2026. The itinerary includes ten sea days alongside visits to Hawaii, allowing travelers to explore Pearl Harbor or embark on nature walks.
In French Polynesia, you can snorkel in crystal-clear waters, and take scenic drives while enjoying overnight stays that extend your escape from reality. Crystal’s gourmet dining options make for delightful onboard culinary experiences, and recent refurbishments have enhanced passenger accommodations.
Who should book: Most suitable for sophisticated travelers seeking personalized service and upscale dining experiences.
8-night Mexican Riviera cruise with Carnival Cruise Line
Carnival Cruise Line presents an exciting Mexican Riviera sailing round-trip from Long Beach. Enjoy excursions such as kayaking past El Arco in Cabo San Lucas or salsa dancing and cooking in Mazatlan.
The Carnival Panorama offers an impressive mix of activities and amenities for families, including a trampoline park and an adults-only area for relaxation. Dining options range from fine steakhouse experiences to casual bites, ensuring there’s something for every palate.
Who should book: This cruise appeals to families on a budget seeking fun and varied activities for all ages.
6-night Pacific Coastal sailing with Celebrity Cruises
Head north with Celebrity Cruises on a six-night sailing that takes you to exquisite destinations like San Francisco, Astoria, and Victoria, BC. Opportunity awaits in each port, such as visiting iconic landmarks or indulging in afternoon tea at Fairmont Empress.
Celebrity Summit, capable of accommodating 2,200 guests, is lauded for its culinary offerings—including interactive dining at Le Petit Chef—and luxurious wellness amenities. Guests can enjoy dedicated butler service in The Retreat suite and an array of onboard activities that cater to both relaxation and engagement.
Who should book: Ideal for travelers appreciating a refined cruise experience with gourmet dining and elegant accommodations.
19-night Los Angeles to Vancouver sailing with Silversea Cruises
Instead of a straightforward cruise, Silversea Cruises offers a unique April 2025 itinerary taking 19 days, with extensive stops in Hawaii. Highlights include visits to Volcanoes National Park and guided tours of scenic wonders like Waimea Canyon and Pearl Harbor.
The 596-passenger Silver Moon provides an intimate cruise experience where personalized service shines. With an emphasis on luxury, passengers will enjoy spacious suites, top-notch culinary offerings, and exclusive onboard activities designed to engage and delight.
Who should book: Sophisticated travelers in search of a luxurious experience with personalized service and all-inclusive pricing.
